Recorded: 31 May 2003
Oh, in the conduct of the research…, I think this view that we can only understand biology, even the complex biology in the human, only in the light of evolution and only, meaning currently studied through model systems and model organisms. And the fact that we really have to look at the genome as a whole because that’s how nature looks at it is a much, much more dominant thought than it was in 1986.
And, in fact, in retrospect one might even say that studying single things one by one as most of us did before that, there probably wouldn’t have led to a great amount of understanding. So that I think was a seed change in belief that has happened over the last fifteen years.
Aravinda Chakravarti received his Ph.D. in Human Genetics from the Graduate School of Biomedical Sciences at the University of Texas Health Science Center, Houston (1979). After a postdoctoral year at the University of Washington in Seattle, he joined the faculty at the University of Pittsburgh in the Department of Biostatistics and later the Department of Human Genetics as a professor.
In 1994 he moved to Case Western Reserve as Professor of Genetics and Medicine to apply genomic and computer-based methods to study common diseases that arise from a combination of genetic and non-genetic factors.
Dr Chakravarti is one of the Editors-in-Chief of Genome Research, and serves on the Advisory and Editorial Boards of numerous national and international journals and societies. He is a past member of the NIH National Advisory Council of the National Human Genome Research Institute and has chaired the NIH Subcommittee in the 3rd 5-year Genome Project Plan, and continues to serve on several NIH panels.
In 2000 he became Professor of Medicine at The Johns Hopkins School of Medicine and was named director of their new McKusick-Nathans Institute of Genetic Medicine, where he is currently the Henry J. Knott Professor and Director.