Renato Dulbecco on Genome Sequencing
  Renato Dulbecco     Biography    
Recorded: 22 Feb 2011

Well that's, uh, you form your mind to think life. And if you think, what is life? And if you think of the factors involved in the world to, I mean you have to concentrate on the genome of the on the genome. Because those are the ... you can't avoid it. If you decide to make a life which doesn't take into account all of the genes, I think it will be very, very poor. That's certainly going to be ridiculous. So I mean it's obvious, in a way, that if we are interested in our life, in respect to our lives, we have to be, to look at the basic aspects, which are the genes. The genome.

Fundamentally after years of thinking, and operating, and so on, arrived at that conclusion. That really, it was the most full thing in our life is the genome. So, and once we reached this conclusion, then what are you to do? Work on the genome.

There are different reasons for being interested in the genome. Fundamentally, the two main types, there would be one, one would be just to understand the normal operation of the body, the mind, and so on. And the other is how to influence, how to modify, how to favor various … so there are two, part one is an observer, and the total observe very carefully the many details. And the other is how to influence, and in which case see whether there are aspects or interesting, who were important in your point of view. Try to encourage there development for these parts.

In general there are two aspects, one is to understand how they function, the genome. The other is to, how to influence, how to modify. So that depends on your interest. If you're interested in, especially if, say if you're a geneticist, you're interested in the genes, in genetics. So for you the genome is all of these genes. If you are a, somebody who works on, try to develop cancer, then what is important for you is what role does the genome have in cancer. There's lots of work going in that field.

Renato Dulbecco was born in Catanzaro,Italy, in 1914. He studied medicine in Turin before joining the Italian Resistance movement against Benito Mussolini during theSecond Wold War.

After the war Dulbecco emigrated to the United States and worked with Salvador Luria at the University of Indiana before moving on to the University of California.

Won the Albert Lasker Basic Medical Research Award in 1964.

Won the 1975 Nobel Prize in medicine or physiology with David Baltimore and Howard Temin "for their discoveries concerning the interaction between tumor viruses and the genetic material of the cell".