Jennifer Doudna on Undergraduate Participation in Research Projects
  Jennifer Doudna     Biography    
Recorded: 17 Aug 2023

I tried several different projects, but the one that really stood out for me was working one summer for my biochemistry professor on a project to study how bacteria communicate with each other, how the cells actually talk to each other to allow the cells to survive under conditions of starvation. These cells will tend to aggregate, if you're growing them on an agar plate, they will aggregate together and form fruiting bodies and the question that we were trying to answer was, what's the chemical nature of that? How do the cells tell each other, hey, we should all move in this direction and inform this structure? So, it was a lot of fun. It involved a lot of purifying molecules and running mass specs and trying to figure out their structure. It was exactly the kind of thing that I wanted, I felt like I wanted to do when I got to college.

Dr. Jennifer Doudna is a biochemist and 2020 Nobel Prize winner in chemistry. She is also the Li Ka Shing Chancellor’s Chair in Biomedical and Health sciences as well as a professor of biochemistry, biophysics, and structural biology. Her work focuses on RNA interference and gene editing.

In 1985, she earned her Bachelor of Arts degree in biochemistry from Pomona College and in 1989 received her PhD in biological chemistry and molecular pharmacology from Harvard Medical School. From 1991 to 1994, she was a Lucille P. Markey post-doctoral scholar in Biomedical science at the University of Colorado Boulder. She also received fellowships from the Massachusetts General Hospital and Harvard Medical School.

From 1994 to 2001, Dr. Doudna was an associate professor and full professor at Yale University. In 2002, Dr. Douda accepted a professor of biochemistry and molecular biology position at the University of California, Berkeley. She has also been researching with the Howard Hughes Medical Institute since 1997, and her work with CRISPR-Cas9 and other genome-engineering techniques has led to breakthroughs in human and agricultural genomics research. At the Doudna Lab, researchers focus on determining mechanisms of novel genome editing tools for in vitro usage in plants and mammals as well as anti-CRISPR agents.

Dr. Doudna has received numerous awards for her work including the 2020 Nobel Prize in chemistry for developing a method for genome editing, the 2015 Breakthrough Prize in Life Sciences, the 2016 Japan Prize, the 2019 Welfare Betterment Prize, the 2020 Wolf Prize in Medicine, and the 2025 National Medal of Technology and Innovation. She is also a member of the National Academy of Sciences, the National Academy of Medicine, the National Academy of Inventors, and a member of the Royal Society.

SCIENTISTS SPEAKING ABOUT BECOMING A SCIENTIST
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