Martin Reese on Whole Genome Analysis: Identifying Disease Genes
  Martin Reese     Biography    
Recorded: 08 May 2008

Yes. What we did is, so the Alzheimer, when he basically didn’t release his data on the ApoE gene, so we couldn’t really go much into that detail. We did one common disease which was cardiovascular disease. So we looked comprehensively what was known in the literature for all the publications on cardiovascular disease. And we sort of tried to make an initial profile on cardiovascular markers and how we would fear in that one. I have to tell you it’s the really early days. Research isn’t there yet, we’re not really there yet. We don’t really know, we can’t really explain all the genetics. But I think we can do some, so we just try. And we thought of conceptually, we want to know how it works. So we analyzed, I think, twenty-five cardiovascular markers for him, all the very prominent ones. And very interestingly the results where he carried some of them, even for some there was contradictory data. So that again tells us that our information is not ready yet. But in average, he was right in the middle. So what that tells us he’s not protected from cardiovascular disease, but he’s not very high risk now. This is some medical advice and clinical advice. And again I have to put very big error bars on, because we don’t really know, and it’s very early data on this. But it gives us some idea what we did.

Martin Reese is the Co-founder, Chief Executive Officer, and Chairman of the Board of Omicia.

Dr. Martin Reese is an internationally recognized expert in medical informatics and bioinformatics with a track record of bringing strong, grounded scientific knowledge to the corporate sector. Prior to founding Omicia, Dr. Reese served as Vice President of Discovery Informatics for ValiGen. He organized the state-of-the-art Genome Annotation Assessment Project and was a member of the Berkeley Drosophila Genome Project. This project provided the essential proof-of-concept platform for Celera's famous shotgun sequencing technology, which is now internationally recognized - as driving a new standard of excellence in sequencing. It was while at the Lawrence Berkeley National Laboratories that Dr. Reese developed gene-finding algorithms for the Human Genome Project. He holds a Masters degree in Medical Informatics from the University of Heidelberg and a Ph.D. in Genetics jointly from the University of California, Berkeley and the University of Hohenheim, Germany.