Nicholas Wade on Changes in the Human Genome Project
  Nicholas Wade     Biography    
Recorded: 30 May 2003

The field has just grown and grown. It's become the basis of many new fields of science. And people keep inventing new fields of science with something "-omic" at the end - transcriptomics or whatever. Bioinformatics has flowered since all these genome sequences became available. So the genome has already had a deep impact on science, I would say. It has enabled many labs to change the scale of their operations completely, from working on a one-gene-at-a-time basis to a whole-genome basis.

That development in turn has generated a volume of data that only computers can deal with. People are beginning to think about how they might compute the behavior of the cell, now that we are beginning to see how all its component parts interact as one giant integrated system. So with that knowledge in hand you can then start trying to compute how a cell will behave. Given these inputs, what will the cell's output be? And then if you can do that for one cell maybe you can do it for a whole organism, one day in the far distant future.

Nicholas Wade received a B.A. in natural sciences from King's College in Cambridge (1964). He was deputy editor of (italics) Nature magazine in London and then became that journal's Washington correspondent. He joined (italics) Science magazine in Washington as a reporter and later moved to (italics)The New York Times, where he has been an editorial writer, concentrating his writing on issues of defense, space, science, medicine, technology, genetics, molecular biology, the environment, and public policy, a science reporter, and science editor. He is the author or coauthor of several books including (italics) LIFE SCRIPT: How The Human Genome Discoveries Will Transform Medicine And Enhance Your Health (2002).

Covering the Human Genome Project for the (italics) New York Times since 1990, Wade has interviewed Watson on various occasions and visited Cold Spring Harbor for the annual Genome symposium.