Klar & Strathern on The Yeast Group At The NCI Center For Cancer Research
  Klar & Strathern     Biography    
Recorded: 01 May 2000

Amar: I joined him, Jeff, and another colleague Steve Hughes. The Cold Spring Harbor people… they opened another niche some place: It’s kind of good.

Jeff: There was a lot of that aspect that when I came here as a lab director in 1984, with no laboratory to direct, I had positions to hire. I had this wonderful experience at Cold Spring Harbor. That’s what I wanted to try and duplicate. How could we create an atmosphere where the sections—the people involved interacted directly daily? We’re actually sitting in one of the outgrowths of that vision. There is almost nothing better for science than beer and coffee. And this is the coffee room and there is a black board here. No one should have to go more than 100 feet to get to a colleague that will be excited about an observation that they made.

Amar Klar and Jeff Strathern worked together in the Cold Spring Harbor Yeast group from 1977 till 1984 where they made outstanding discoveries about the mechanism of mating type switching in yeast.

Amar Klar, is a leading yeast geneticist, concerned with the molecular biology of gene silencing and mating-type switching. Klar came from India to the University of Wisconsin in 1975 to receive his Ph.D. in bacteriology. From 1977 to 1984, he worked with Jeff Strathern and Jim Hicks in the Cold Spring Harbor Yeast Group studying the mechanism of mating type switching. Klar served as Director of the Delbruck laboratory from 1985 to 1988.

He left Cold Spring Harbor to join the ABL-Basic Research Program as Head of the Developmental Genetics Section. In 1999, Klar joined the National Cancer Institute Center for Cancer Research and is now a Principal Investigator in the Gene Regulation and Chromosome Biology Laboratory at NCI-CCR.

Jeffrey Strathern, a leading yeast geneticist, obtained his Ph.D. from the Molecular Biology Institute at the University of Oregon in 1977 and then moved to Cold Spring Harbor Laboratory, where he became a Senior Staff Member with the yeast genetics laboratory.

In 1984, he joined the ABL-Basic Research Program at the NCI-FCRDC. His research remains centered on aspects of gene regulation and genetic recombination as revealed by studies in yeast. In 1999, Strathern joined the Division of Basic Sciences, NCI. Strathern worked together with Amar Klar and Jim Hicks in the Cold Spring Harbor Yeast group from 1977 to 1984 where they made outstanding discoveries about the mechanism of mating type switching in yeast.