Cold Spring Harbor Symposia on Quantitative Biology
XXIX: Human Genetics
1964
CSHL Digital Photo Archives
1964




Between symposia sessions, 1964



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Human Genetics

Symposium Volume XXIX Contents

Foreword    v

List of Previous Volumes    vi

Photographs of Some Symposium Participants    vii

List of Those Attending the Symposium    ix


TH. DOBZHANSKY. Opening Address: Human Genetics - An Outsider's View    1



POPULATION STUDIES

CAVALLI-SFORZA, L. L., I. BARRAI and A. W. F. EDWARDS. Analysis of Human Evolution under Random Genetic Drift    9

NEWCOMBE, H. B. Pedigrees for Population Studies - A Progress Report    21

FREIRE-MAIA, N. On the Methods Available for Estimating the Load of Mutations Disclosed by Inbreeding    31

SUTTER, J. and J. M. GOUX. Lethal Equivalents and Demographic Measures of Mortality    41

HIRAIZUMI, Y. Prezygotic Selection as a Factor in the Maintenance of Variability    51

SLATIS, H. The Study of Normal Variation in Man. II. Polymorphism and Pleiotropy    61

MORTON, N. E. Genetic Studies of Northeastern Brazil    69

DRONAMRAJU, K. R. Mating Systems of the Andhra Pradesh People    81

NEEL, J. and F. SALZANO. A Prospectus for Genetic Studies of the American Indian    85

MCKUSICK, V. A., J. A. HOSTETLER, J. A. EGELAND, and R. ELDRIDGE. The Distribution of Certain Genes in the Old Order Amish    99

GOLDSCHMIDT, E. and T. COHEN. Inter-ethnic Mixture among the Communities of Israel    115

GAJDUSEK, D. C. Factors Governing the Genetics of Primitive Human Populations    121

ALLISON, A. C. Polymorphism and Natural Selection in Human Populations    137



GENETICS OF SOMATIC CELLS AND CELLS IN CULTURE

SZYBALSKI, W. Chemical Reactivity of Chromosomal DNA as Related to Mutagenicity : Studies with Human Cell Lines    151

LITTLEFIELD, J. W. The Selection of Hybrid Mouse Fibroblasts    161

PUCK, T. T. Studies of the Life Cycle of Mammalian Cells    167

GLASS, B. The Study of Gene and Chromosome Mutations in Human and Other Mammalian Cell Cultures    177

ABEL, P. Evidence for the Universality of the Genetic Code    185

KROOTH, R. S. Properties of Diploid Cell Strains Developed from Patients with an Inherited Abnormality of Uridine Biosynthesis    189

KOLER, R., R. BIGLEY, R. T. JONES, D. A. RIGAS, P. VANBELLINGHEN, and P. THOMPSON. Pyruvate Kinase: Molecular Differences between Human Red Cell and Leukocyte Enzyme    213

DE CARLI, L., J. J. MAIO, F. NUNNO, and A. S. BENERECETTI. Cytogenetic Studies with Alkaline Phosphatase in Human Heteroploid Cells    223

COX, R. P. and C. M. MACLEOD. Regulation of Alkaline Phosphatase in Human Cell Cultures    233

GARTLER, S. M. and D. LINDER. Selection in Mammalian Mosaic Cell Populations    253

BEUTLER, E. Gene Inactivation: The Distribution of Gene Products among Populations of Cells in Heterozygous Humans    261

KLEIN, E. Transplantation Antigens as Markers in Somatic Cell Genetics    273

PAYNE, R., M. TRIPP, J. WEIGLE, W. BODMER, AND J. BODMER. A New Leukocyte Isoantigen System in Man    285



HUMAN PROTEINS

JONES, R. T. Structural Studies of Aminoethylated Hemoglobins by Automatic Peptide Chromatography    297

SMITHIES, O. Chromosomal Rearrangements and Protein Structure    309

GIBLETT, E. Variant Haptoglobin Phenotypes    321

HUEHNS, E. R., N. DANCE, G. H. BEAVEN, F. HECHT, and A. G. MOTULSKY. Human Embryonic Hemoglobins.    327

BOYER, S. H., P. HATHAWAY, and M. D. GARRICK. Modulation of Protein Synthesis in Man: An in vitro Study of Hemoglobin Synthesis by Heterozygotes    333

BAGLIONI, C. and B. COLOMBO. Control of Hemoglobin Synthesis    347

ZUCKERKANDL, E. Compensatory Effects in the Synthesis of Hemoglobin Polypeptitde Chains    357

KOSSMAN, R. J., D. C. FAINER, and S. H. BOYER. A Study of Myoglobin in Disease with Comments Concerning the Myoglobin Minor Components    375

HUEHNS, E. R., D. J. WEATHERALL, R. H. DE BELLIS, L. LUZZATTO. General Discussion: Human Proteins    387

KIRKMAN, H. N., P. R. MCCURDY, and J. L. NAIMAN. Functionally Abnormal Glucose-6-Phosphate Dehydrogenases    391

MOTULSKY, A. G. Current Concepts of the Genetics of the Thalassemias    399

NANCE, W. E. Genetic Tests with a Sex-linked Marker: Glucose-6-Phosphate Dehydrogenase    415

ROSENFIELD, R. E., I. O. SYZMANSKI, and KOCHWA. Immunochemical Studies of the Rh System. III. Quantitative Hemagglutination that is Relatively Independent of Source of Rh Antigens and Antibodies    427

BEARN, A. G., B. H. BOWMAN, and F. D. KITCHEN. Genetic and Biochemical Considerations of the Serum Group-Specific Component    435

KUNKEL, H. G., J. C. ALLEN, and H. M. GREY. Genetic characters and the Polypeptide Chains of Various Types of Gamma Globulin    443

STEINBERG, A. G. Population, Immunogenetic, and Biochemical Studies on the Gm(b) Factors of Human Gamma Globulin    449

HERZENBERG, L. A. A Chromosome Region for Gamma2a and Beta 2A Globulin H Chains Isoantigens in the Mouse    455

FUDENBERG, H. H., E. R. STEIHM, E. C. FRANKLIN, M. MELTZER, and B. FRANGIONE. Antigenicity of Heretiary Human γ-Globulin (Gm) Factors - Biological and Biochemical Aspects    463

GLASS, B. Summary and Concluding Remarks    473






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