Program
Session 1: Welcome and Introductory Session
- Stanley Falkow
- Early history of Plasmid Biology
- Stanley N. Cohen
- Plasmid breakout into mainstream biology
- Richard Novick
- Plasmid Diversity and Evolution
Session 2: Antibiotic resistance
Chair: Chris Thomas, University of Birmingham, UK
- Julian Davies
- Antibiotic resistance and the end of antibiotics
- George A. Jacoby
- Plasmids: Acquisitive and ubiquitous
Session 3: Bacterial toxins and microcins: plasmids and pathogenicity
Chair: George Jacoby, Lahey Clinic, Burlington, MA
- John Mekalanos
- Turf war: plasmid-encoded virulence and microbiome competitive factors
Session 4: Plasmid host range and evolution
Chair: Roy Curtiss III, Arizona State University, Tempe, AZ
- Eva Top
- The plasticity of plasmid host range
- Bruce Levin
- A perspective on the population and evolutionary biology of plasmids
Session 5: The Nature of plasmids
Chair: Barbara Funnell, University of Toronto, Ontario, Canada
- David Summers
- The structural fluidity of plasmids and its consequences for genetic stability
- Don Clewell
- Plasmid circles: relaxed and otherwise
- Peter Barth
- From stamp collecting to genetic manipulation
Session 6: Transposition & genetic recombination
Chair: John Mekalanos, Harvard Medical School, Boston,MA
- David Sherratt
- From rolling circles and multimer resolution in plasmid ColE1 to jumping genes and chromosomes
- Mike Chandler
- Plasmids and Transposition
Session 7: Plasmid-borne genes and metabolic functions
Chair: Gerhart Wagner, Uppsala University, Sweden
- Ananda Chakrabarty
- Degradative plasmids: a path to intellectual property for biotechnology
Roundtable: Historians and scientists views and general discussion on the role of plasmids in the overall history of the biological sciences
Chair: Jan Witkowski, Cold Spring Harbor Laboratory, NY
- R. Curtiss III
- Roundtable
- Mathias Grote
- Roundtable
- Mark Jones
- Roundtable
Session 8: Plasmids and plants
Chair: Julian Davies, University of British Columbia, Vancouver, Canada
- Marc van Montagu
- From TIP and Ti-plasmid to plant genetic engineering and plant-microbe interactions
- Peter Young
- Natural Diversity of Plant Plasmids
- Susana Brom
- From “Knöllchen” to structured symbiotic plasmids
Session 9: Plasmid DNA replication
Chair: Susana Brom, Universidad Nacional Autonóma de México, Cuernavaca, Mexico
- Saleem Khan
- Plasmid rolling-circle replication: conservative or liberal?
- Gerhart Wagner
- Copy number control by antisense RNA: learning the rules
Session10: Interbacterial transferability
Chair: Dhruba Chattoraj, National Cancer Institute, Bethesda, MD
- Laura Frost
- F plasmid transfer: new tricks for an old dog
- Fernando de la Cruz
- Bacterial conjugation: from infectious sex to computer wires
Session 11: Stability, partitioning, and post-segregation lethality
Chair: David Sherratt, University of Oxford, UK
- Barbara Funnell
- Plasmid stability and partition:variations on a theme
- Michael Yarmolinsky
- Death and Addiction
Session 12: Plasmids as whole systems
Chair: Eva Top, University of Idaho, Moscow, ID
- Chris Thomas
- Plasmids as integrated systems
- Dhruba Chattoraj
- Plasmids in and as chromosomes: integration and evolution
Discussion: Future directions in plasmid biology
Chair: Lead by meeting organizers,
