The former J.W.T. Nichols CSH estate, known as Uplands Farm, had been deeded to the Long Island Chapter of the Nature Conservancy. In 1984, the Laboratory made a leasing agreement with the Nature Conservancy to purchase 12 acres and then finalized the purchase in May of 1988.

The Uplands Farm experimental station consists of a cytogenetics laboratory, a research greenhouse, two residences, and fertile fields for growing maize.