Studies on Mouse Leukemia, 1930s

During his time at Cold Spring Harbor, Carnegie scientist, E. Carlton MacDowell, discovered a strain of mice predisposed to spontaneous leukemia. Subsequent breeding experiments lead to the development of mice with increased susceptibility or resistance to the cancer. This work laid the foundation of modern cancer research. He published a series of papers on his work, which are still available for reading on PubMed.

 

E. Carlton MacDowell (front right) with his staff: J. Potter, M. Findley, and M. Taylor, 1935

 

Paper presented by E.C.MacDowell and M. Richter, 1932