Evelyn Witkin

Evelyn Maisel Witkin was born in New York City on March 9, 1921. She was awarded her Bachelor of Arts degree from New York University, Majoring in Zoology, in 1941. Witkin began her graduate studies with Theodosium Dobzhansky at Columbia University. Her interests changed from Drosophila genetics to bacterial genetics and she spent the summer of 1944 at Cold Spring Harbor; where she isolated a radiation-resistant mutant of E. coli. Witkin was awarded her Ph.D. in 1947 and remained at the Carnegie Institution of Washington Department of Genetics until 1955. She them moved to the State University of New York Downstate Medical Center in Brooklyn. In 1971 she was appointed Professor of Biology Sciences at Douglass College, Rutgers University, where she was named Barbara McClintock Professor of Genetics in 1979. Witkin moved to the Waksman Institute at Rutgers University in 1983, becoming Barbara McClintock Professor Emerita in 1991.

Witkin's research since the completion of her PhD was based on DNA mutagenesis, her mutagenesis work led to her work on DNA repair. By characterizing the phenotypes of mutagenized E. coli, she and colleague Miroslav Radman (at the time a post-doctoral student at Harvard) detailed the SOS response to UV radiation in bacteria in the early 1970s. She continued to work on the mechanism of the SOS response until she retired in 1991.[1] The SOS response to DNA damage was a seminal discovery because it was the first coordinated stress response to be elucidated.

Among her many awards are membership in the National Academy of Sciences (1977); Fellow of the American Association for the Advancement of Sciences (1980); American Women of Science Award for Outstand Research; and Fellow, American Academy of Microbiology. In 2000 she was awarded the 2000 Thomas Hunt Morgan Medal. She was awarded the Presidential Medal of Science from President George W. Bush in 2002 for her work on mutagenesis and DNA repair, and “For her insightful and pioneering investigations on the genetics of DNA mutagenesis and DNA repair that have increased our understanding of processes as varied as evolution and the development of cancer.”

Charles DeLisi Collection Finding Aid

The finding aid of the Charels DeLisi collection in contained in the attached PDF.

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Charles DeLisi

Charles DeLisi is the Metcalf Professor of Science and Engineering at Boston University. Prior to moving to Boston University, he was Professor and Chair of Biomathematical Sciences and Professor of Molecular Biology at the Mount Sinai School of Medicine (1987–1989), Director of the United States Department of Energy's Health and Environmental Research Programs (1985–1987), Section Chief at National Institutes of Health (1975–1985), and Theoretical Division Staff Scientist at Los Alamos National Laboratory (1972–1975).

In 1999 he initiated the Boston University graduate program in Bioinformatics, which now includes approximately 120 students and 50 faculty from across the university.

In 1985, as Director of the U.S. Department of Energy’s (DOE) Health and Environmental Research Programs, DeLisi and his advisors proposed, planned and defended before the White House Office of Management and Budget and the Congress, the Human Genome Project. The proposal created a storm of controversy, but was included in President Ronald Reagan’s FY 1987 budget submission to the Congress, and subsequently passed both the House and the Senate, the latter with the essential support of Senator Pete Domenici (R, NM).

DeLisi is recipient of numerous awards including the Presidential Citizens Medal, awarded to him by President Clinton for his seminal role in initiating the Human Genome Project.

For more information regarding Charles DeLisi and the 1986 Santa Fe meeting, please refer to Nature 455, 876-877 (16 October 2008) | Meetings that changed the world: Santa Fe 1986: Human genome baby-steps.”http://www.nature.com/nature/journal/v455/n7215/full/455876a.html


About Personal Collections

HersheyDedication1979CSHL Archives’ mission is to collect and document both the history of science at Cold Spring Harbor, and the history of molecular biology and genetics in general. We are home to the personal collections of numerous notable scientists, including Nobel laureates James D. Watson, Barbara McClintock, Alfred Hershey, Walter Gilbert, and Hermann Muller. Our collections date back to the early days of scientific research at Cold Spring Harbor, including Charles Davenport (first director of the Carnegie Institution of Washington Department of Genetics), Reginald Harris (first director of Long Island Biological Association), and Hugo Fricke (radiation scientist at CSH from 1928-1955). The Archives also contains the personal collections of recent CSHL scientists, such as yeast geneticists Amar Klar, James Hicks, and Jeffrey Strathern, as well history of science scholars, such Elof Carlson and Errol Friedberg. Our collections generally consist of correspondence, photographs, laboratory notebooks, administrative files, memorabilia, and audiovisual media.

CSHL Meetings Abstracts Inventory

CSHL Meetings Abstracts Inventory

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Winship Herr

Winship Herr was born in 1958 in New Haven, CT.  In 1974, he obtained his A.B. (Biology) at University of California at Santa Cruz and received his PhD from Harvard University in 1982 for studies on recombinant retroviruses in leukemogenic mice with Walter Gilbert. After postdoctoral studies with Frederick Sanger in Cambridge, England and then with Joe Sambrook at Cold Spring Harbor Laboratory, he joined the CSHL faculty in 1984. After achieving the rank of Senior Scientist, he served as assistant director of the Laboratory from 1994-2002 and from 1998-2004 was the founding Dean of the Watson School of Biological Sciences, a doctoral degree-granting school. In 2004, he joined the Center for Integrative Genetics in Lausanne, Switzerland.

The Winship Herr Collection is comprised mainly of material generated from 1991 to 1994.  At CSHL, Dr. Herr’s work focused on the mechanics of transcriptional regulation in eukaryotes utilizing two cellular proteins, Oct-1 and Oct-2 and a herpes simplex protein, VP16.

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